Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160423 | 1.00 | GPR119 (0.47) | GPR119ITGB3ITGA2BCRBNHDAC4 | |
| SCHEMBL12160457 | 1.00 | GPR119 (0.47) | GPR119ITGB3ITGA2BCRBNHDAC4 | |
| SCHEMBL12160456 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL12106786 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL14621357 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2B | |
| SCHEMBL12160421 | 0.84 | GPR119 (0.48) | GPR119ITGB3ITGA2BCRBNSCN9A | |
| SCHEMBL12160382 | 0.84 | CRBN (0.51) | GPR119ITGB3ITGA2BCRBNSCN9A | |
| SCHEMBL12160488 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL1575678 | 0.83 | GPR119 (0.64) | GPR119 | |
| SCHEMBL12160463 | 0.83 | GPR119 (0.47) | GPR119ITGB3ITGA2BCRBNSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2383270-A1 | Piperidine GPCR agonists | Prosidion Limited (GB) | 2011-11-02 | — | — | EP | disclosed |
| WO-2007003962-A2 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |