Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064331 | 0.87 | PTGS2 (0.39) | RXRARXRBTRPA1PTGS2HSPA5 | |
| SCHEMBL608438 | 0.87 | ACHE (0.48) | ACHERXRARXRBTRPA1PRKCA | |
| SCHEMBL8231933 | 0.87 | ACHE (0.48) | ACHERXRARXRBTRPA1PRKCA | |
| SCHEMBL16961327 | 0.81 | CYP4F2 (0.48) | ACHERXRARXRBTRPA1PRKCA | |
| SCHEMBL16952582 | 0.78 | PGK1 (0.41) | ACHERXRARXRBTRPA1PRKCA | |
| SCHEMBL12119353 | 0.78 | ACHE (0.67) | ACHERXRARXRBTRPA1PRKCA | |
| SCHEMBL23429131 | 0.76 | ACHE (0.39) | ACHERXRARXRBTRPA1PRKCA | |
| SCHEMBL2620706 | 0.76 | PTGS2 (0.37) | RXRARXRBPTGS2 | |
| SCHEMBL16960040 | 0.76 | ACHE (0.39) | ACHERXRARXRBTRPA1PRKCA | |
| SCHEMBL16957078 | 0.76 | CNR1 (0.39) | ACHERXRARXRBTRPA1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386559-A1 | Cytotoxiv agents comprising new tomaymycin derivatives and their therapeutic use | SANOFI (FR) | 2011-11-16 | — | — | EP | disclosed |