Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 3/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023516 | 0.88 | THRA (0.59) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL1988903 | 0.85 | THRA (0.64) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL5469281 | 0.85 | ALDH1A1 (0.52) | PPARGPPARATHRATHRBPTPN11 | |
| SCHEMBL10944158 | 0.84 | THRA (0.66) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL15153314 | 0.84 | THRA (0.66) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL11245935 | 0.84 | THRA (0.66) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL7171001 | 0.84 | THRA (0.66) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL11705230 | 0.84 | THRA (0.66) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL2341095 | 0.82 | KMT2A (0.55) | THRATHRBPTPN11TP53TSHR | |
| SCHEMBL7166122 | 0.78 | THRA (0.53) | THRATHRBPTPN11TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114931-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2011-11-02 | — | — | EP | disclosed |