Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 8/20 | 0.53 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317521 | 0.88 | ACLY (0.68) | ACLYKCNMA1SERPINE1GRIK1SUCNR1 | |
| SCHEMBL12121824 | 0.84 | HDAC1 (0.46) | ACLYKCNMA1HDAC1MEN1KMT2A | |
| SCHEMBL12165987 | 0.84 | HDAC1 (0.56) | ACLYKCNMA1HDAC1KDM4EHDAC2 | |
| SCHEMBL12166011 | 0.82 | ACLY (0.48) | ACLYKCNMA1SERPINE1GRIK1MEN1 | |
| SCHEMBL1315511 | 0.80 | ACLY (0.50) | ACLYKCNMA1HDAC1SERPINE1GRIK1 | |
| SCHEMBL12166119 | 0.79 | HDAC1 (0.42) | ACLYKCNMA1HDAC1NPSR1RXFP1 | |
| SCHEMBL1315890 | 0.79 | ACLY (0.67) | ACLYKCNMA1HDAC1SERPINE1GRIK1 | |
| SCHEMBL14429560 | 0.79 | HTT (0.55) | ACLYHDAC1KDM4EHDAC2 | |
| SCHEMBL12166105 | 0.79 | HDAC1 (0.51) | ACLYKCNMA1HDAC1KDM4EHDAC2 | |
| SCHEMBL1320352 | 0.78 | ACMSD (0.68) | ACLYKCNMA1HDAC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385036-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |