Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12166052 | 0.89 | KDM4E (0.47) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL12166031 | 0.89 | KMT2A (0.46) | POLBAKR1C2AKR1C1KDM4EMAPT | |
| SCHEMBL12166018 | 0.89 | MEN1 (0.46) | POLBAKR1C2AKR1C1KDM4EMAPT | |
| SCHEMBL12166134 | 0.89 | KDM4E (0.46) | AKR1C2AKR1C1KDM4EMAPTMEN1 | |
| SCHEMBL12121662 | 0.86 | KDM4E (0.44) | AKR1C2AKR1C1KDM4EMAPTMEN1 | |
| SCHEMBL12121644 | 0.85 | LMNA (0.57) | LMNAPOLBNPSR1AKR1C2AKR1C1 | |
| SCHEMBL12121825 | 0.83 | ALDH1A1 (0.43) | AKR1C2AKR1C1KDM4EMAPTMEN1 | |
| SCHEMBL12121815 | 0.82 | KDM4E (0.40) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL12121811 | 0.80 | LRRK2 (0.41) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL12121294 | 0.80 | PTGES (0.43) | KDM4EMAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385036-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |