Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12166093 | 0.88 | DDB1 (0.33) | MAPTALDH1A1DDB1CRBNKDM4E | |
| SCHEMBL1894782 | 0.86 | TSPO (0.38) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL12166116 | 0.78 | HSD17B10 (0.44) | MAPTMEN1MAPK1KMT2AKDM4E | |
| SCHEMBL12166087 | 0.77 | ACHE (0.35) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL12166118 | 0.77 | TSPO (0.38) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL12166092 | 0.76 | KRAS (0.35) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL12166126 | 0.74 | TSPO (0.39) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12166124 | 0.71 | TSPO (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1893467 | 0.71 | TSPO (0.42) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12166010 | 0.71 | MAOA (0.44) | ALDH1A1DDB1CRBNKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012599-B2 | Nitrogen-containing condensed heterocyclic compounds for OLEDs | MERCK PATENT GMBH (DE) | 2015-04-21 | — | — | US | disclosed |
| US-9012599-B2 | Nitrogen-containing condensed heterocyclic compounds for OLEDs | MERCK PATENT GMBH (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20120232241-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUNDS FOR OLEDS | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2012-09-13 | — | — | US | disclosed |
| US-20120232241-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUNDS FOR OLEDS | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2012-09-13 | — | — | US | disclosed |
| WO-2011060867-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUNDS FOR OLEDS | MERCK PATENT GMBH (DE) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232241-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUNDS FOR OLEDS | OCIAD2, OCIAD1, ODC1 | MAPT 1802/4885ALDH1A1 1351/4885MEN1 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.