SCHEMBL12166392

SCHEMBL12166392

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(C4(c5cccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5)c5ccccc5Sc5ccccc54)c3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
MEN1 O00255 7/20 0.36
KMT2A Q03164 7/20 0.36
MAPT P10636 4/20 0.36
HPGD P15428 4/20 0.36
ALDH1A1 P00352 3/20 0.36
LMNA P02545 3/20 0.35
KDM4E B2RXH2 2/20 0.35
GLA P06280 1/20 0.35
ADORA2A P29274 5/20 0.33
ADORA1 P30542 4/20 0.33
MAPK1 P28482 3/20 0.33
ADORA3 P0DMS8 2/20 0.33
ADORA2B P29275 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.33
WHR1 P49842 1/20 0.33
NTSR1 P30989 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12166381 0.97 L3MBTL1 (0.35) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL12166389 0.93 MEN1 (0.32) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL12166390 0.93 GP6 (0.35) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL12166385 0.93 GP6 (0.35) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL12166382 0.92 GP6 (0.34) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL12166399 0.92 L3MBTL1 (0.30) L3MBTL1KMT2A
SCHEMBL12166372 0.91 L3MBTL1 (0.35) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL12166348 0.89 L3MBTL1 (0.38) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL12166379 0.89 BACE1 (0.31)
SCHEMBL21152427 0.89 MEN1 (0.43) L3MBTL1MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-10981880-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-04-20 US disclosed
US-20190169139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-06-06 US disclosed
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-04-07 US disclosed
US-9187456-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885MEN1 665/4885KMT2A 2454/4885
US-10981880-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885MEN1 665/4885KMT2A 2454/4885
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885MEN1 665/4885KMT2A 2454/4885
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885MEN1 665/4885KMT2A 2454/4885
US-11760734-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885MEN1 665/4885KMT2A 2454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.