SCHEMBL12166399

SCHEMBL12166399

c1ccc(-c2ncnc(-c3cccc(C4(c5cccc(-c6ncnc(-c7ccccc7)n6)c5)c5ccccc5Sc5ccccc54)c3)n2)cc1

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.30
KMT2A Q03164 1/20 0.30
CSF1R P07333 1/20 0.30
PDGFRB P09619 1/20 0.30
GSK3A P49840 1/20 0.30
CDK9 P50750 1/20 0.30
CDK5 Q00535 1/20 0.30
ACVR1 Q04771 1/20 0.30
CDK5R1 Q15078 1/20 0.30
TAOK1 Q7L7X3 1/20 0.30
DYRK1B Q9Y463 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12166379 0.97 BACE1 (0.31)
SCHEMBL12166356 0.92 KMO (0.30)
SCHEMBL12166392 0.92 L3MBTL1 (0.37) L3MBTL1KMT2A
SCHEMBL12166354 0.90 L3MBTL1 (0.31) L3MBTL1KMT2ACSF1RPDGFRBGSK3A
SCHEMBL12166381 0.89 L3MBTL1 (0.35) L3MBTL1KMT2A
SCHEMBL12166396 0.86 BACE1 (0.33)
SCHEMBL12166390 0.85 GP6 (0.35) L3MBTL1KMT2A
SCHEMBL12166389 0.85 MEN1 (0.32) L3MBTL1KMT2A
SCHEMBL12166385 0.85 GP6 (0.35) L3MBTL1KMT2A
SCHEMBL12166316 0.85 KMT2A (0.40) L3MBTL1KMT2ACSF1RPDGFRBGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-10981880-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-04-20 US disclosed
US-20190169139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-06-06 US disclosed
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-04-07 US disclosed
US-9187456-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885KMT2A 2454/4885CSF1R 3550/4885
US-10981880-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885KMT2A 2454/4885CSF1R 3550/4885
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885KMT2A 2454/4885CSF1R 3550/4885
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885KMT2A 2454/4885CSF1R 3550/4885
US-11760734-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885KMT2A 2454/4885CSF1R 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.