SCHEMBL12166793

SCHEMBL12166793

C=C(C)C1CC(O)CCC1C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 1/20 0.36
▸ LMNA P02545 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16243671 1.00 CES2 (0.36) CES2LMNACYP2C9
SCHEMBL12166765 0.84 CES2 (0.33) CES2LMNACYP2C9
SCHEMBL25404332 0.83 — —
SCHEMBL25404335 0.83 — —
SCHEMBL19058480 0.79 CES2 (0.37) CES2
SCHEMBL31443059 0.77 CES2 (0.36) CES2LMNA
SCHEMBL14091700 0.77 — —
Alcohol SCHEMBL8535111 0.76 CES2 (0.38) CES2
Alcohol SCHEMBL8535108 0.76 CES2 (0.38) CES2
SCHEMBL12775171 0.76 CES2 (0.38) CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9832995-B2 Microbial composition DOW GLOBAL TECHNOLOGIES LLC (US) 2017-12-05 — — US disclosed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 — — US disclosed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 — — US disclosed
US-9012497-B2 Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE AG (DE) 2015-04-21 — — US disclosed
US-9012497-B2 Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE AG (DE) 2015-04-21 — — US disclosed
US-20140323585-A1 MICROBIAL COMPOSITION DOW GLOBAL TECHNOLOGY LLC 2014-10-30 — — US disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 — — US disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 — — US disclosed
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2013-05-30 — — US disclosed
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2013-05-30 — — US disclosed
EP-2389922-A1 Cyclohexyl carbamate compounds as anti-ageing actives Symrise AG (DE) 2011-11-30 — — EP disclosed
WO-2010122178-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE GMBH & CO. KG (DE) 2010-10-28 — — WO disclosed
WO-2010097479-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE GMBH & CO. KG (DE) 2010-09-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES CBR1, CYP2A13, CBR3 CES2 86/4885LMNA 1211/4885CYP2C9 36/4885
US-20140323585-A1 MICROBIAL COMPOSITION CD14, DRD3, JUND CES2 173/4885LMNA 4623/4885CYP2C9 1010/4885
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS CBR1, NCOR2, CECR2 CES2 7/4885LMNA 2360/4885CYP2C9 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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