SCHEMBL121703

SCHEMBL121703

CCCCOCN1C(=O)NC2NC(=O)N[C@H]21

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.67
ABL1 P00519 3/20 0.67
RIN1 Q13671 3/20 0.67
GAA P10253 2/20 0.43
KDM4E B2RXH2 3/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 2/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723545 1.00 TDP1 (0.67) TDP1ABL1RIN1GAAKDM4E
SCHEMBL723615 0.92 TDP1 (0.59) TDP1ABL1RIN1GAAKDM4E
SCHEMBL721824 0.85 TDP1 (0.60) TDP1ABL1RIN1GAAKDM4E
SCHEMBL723098 0.78 TDP1 (0.57) TDP1ABL1RIN1GAAKDM4E
SCHEMBL192058 0.76 TDP1 (0.68) TDP1ABL1RIN1GAAKDM4E
SCHEMBL725117 0.76 TDP1 (0.54) TDP1ABL1RIN1GAAKDM4E
SCHEMBL721699 0.74 TDP1 (0.53) TDP1ABL1RIN1GAAKDM4E
SCHEMBL11145933 0.72 TDP1 (0.72) TDP1ABL1RIN1GAAKDM4E
SCHEMBL124787 0.71 GAA (0.42) TDP1ABL1RIN1GAAALDH1A1
SCHEMBL723474 0.70 TDP1 (0.47) TDP1ABL1RIN1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2424350-A1 AGROCHEMICAL FORMULATIONS OF MICROCAPSULES FOR COMPOUNDS CONTAINING CARBOXAMIDE GROUPS Gat Microencapsulation, AG (AT) 2012-03-07 EP claimed
WO-2010124705-A1 AGROCHEMICAL FORMULATIONS OF MICROCAPSULES FOR COMPOUNDS CONTAINING CARBOXAMIDE GROUPS GAT MICROENCAPSULATION, AG (AT) 2010-11-04 WO claimed