SCHEMBL12175604

SCHEMBL12175604

c1ccc(-n2c3ccccc3c3cc4c(cc32)c2ccccc2n4-c2cc(-n3c4ccccc4c4ccccc43)nc(-n3c4ccccc4c4ccccc43)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.60
KDM4E B2RXH2 1/20 0.60
ATM Q13315 1/20 0.60
MAPK1 P28482 2/20 0.38
HTT P42858 2/20 0.38
MAT2A P31153 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
MAPK8 P45983 2/20 0.36
KMT2A Q03164 2/20 0.36
IL1R1 P14778 1/20 0.36
PGR P06401 1/20 0.35
LMNA P02545 1/20 0.35
MAPK9 P45984 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KDR P35968 1/20 0.35
HKDC1 Q2TB90 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027568 0.90 L3MBTL1 (0.60) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL10027576 0.90 L3MBTL1 (0.60) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL4402486 0.89 KDM4E (0.56) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL16452216 0.88 L3MBTL1 (0.50) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL2754616 0.86 L3MBTL1 (0.75) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL19863526 0.86 L3MBTL1 (0.75) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL27426967 0.86 L3MBTL1 (0.82) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL1638441 0.86 L3MBTL1 (0.82) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL10027585 0.85 L3MBTL1 (0.58) L3MBTL1KDM4EATMMAPK1HTT
SCHEMBL17248301 0.85 L3MBTL1 (0.58) L3MBTL1KDM4EATMMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210391548-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2021-12-16 US disclosed
US-20170346025-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-30 US disclosed
US-20170346025-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-30 US disclosed
EP-2564438-B1 DEPOSITING PREMIXED MATERIALS UNIVERSAL DISPLAY CORP (US) 2016-10-19 EP disclosed
US-9040962-B2 Depositing premixed materials UNIVERSAL DISPLAY CORPORATION (US) 2015-05-26 US disclosed
US-9040962-B2 Depositing premixed materials UNIVERSAL DISPLAY CORPORATION (US) 2015-05-26 US disclosed
US-20130112952-A1 DEPOSITING PREMIXED MATERIALS NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-05-09 US disclosed
US-20130112952-A1 DEPOSITING PREMIXED MATERIALS NIPPON STEEL CHEMICAL CO., LTD. (JP) 2013-05-09 US disclosed
WO-2011136755-A1 DEPOSITING PREMIXED MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130112952-A1 DEPOSITING PREMIXED MATERIALS MCM4, MCM2, MCM5 L3MBTL1 2202/4885KDM4E 2235/4885ATM 2676/4885
US-20210391548-A1 ORGANIC LIGHT-EMITTING DEVICE OR51E2, OR10J3, LEF1 L3MBTL1 399/4885KDM4E 1317/4885ATM 2940/4885
US-20170346025-A1 ORGANIC LIGHT-EMITTING DEVICE OR51E2, OR10J3, LEF1 L3MBTL1 399/4885KDM4E 1317/4885ATM 2940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.