Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.74 |
| ▸ | ACP1 | P24666 | 12/20 | 0.74 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.64 |
| ▸ | PTPRF | P10586 | 2/20 | 0.63 |
| ▸ | PTPRB | P23467 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177290 | 0.93 | ENPP2 (0.74) | PTPN1ACP1PTPN2ENPP2PPARG | |
| SCHEMBL12177475 | 0.91 | PPARG (0.73) | PTPN1ACP1PTPN2ENPP2PPARG | |
| SCHEMBL20340001 | 0.90 | NLRP3 (0.81) | PTPN1ACP1PTPN2NLRP3MAPK1 | |
| SCHEMBL20339998 | 0.90 | NLRP3 (0.81) | PTPN1ACP1PTPN2NLRP3MAPK1 | |
| SCHEMBL12177458 | 0.89 | PTPN1 (0.71) | PTPN1ACP1PTPN2ENPP2PTPRF | |
| SCHEMBL12177286 | 0.88 | PPARG (0.76) | PTPN1ACP1PTPN2ENPP2PPARG | |
| SCHEMBL12177742 | 0.87 | PPARG (0.68) | PTPN1ACP1PTPN2ENPP2PPARG | |
| SCHEMBL12177549 | 0.84 | PPARG (0.64) | PTPN1ACP1PTPN2ENPP2PPARG | |
| SCHEMBL12177128 | 0.84 | PTPN1 (0.61) | PTPN1ACP1PTPN2ENPP2PPARG | |
| SCHEMBL12177758 | 0.83 | PPARG (0.82) | PTPN1ACP1PTPN2ENPP2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |