Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.71 |
| ▸ | ACP1 | P24666 | 16/20 | 0.71 |
| ▸ | PTPN2 | P17706 | 11/20 | 0.64 |
| ▸ | PTPRF | P10586 | 2/20 | 0.64 |
| ▸ | PTPRB | P23467 | 2/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177396 | 0.94 | ENPP2 (0.68) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177353 | 0.92 | PIM1 (0.59) | PTPN1ACP1ENPP2 | |
| SCHEMBL12177416 | 0.91 | PTPN1 (0.60) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177549 | 0.90 | PPARG (0.64) | PTPN1ACP1PTPN2ENPP2 | |
| SCHEMBL12177336 | 0.89 | PTPN1 (0.74) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177785 | 0.89 | PIM1 (0.56) | PTPN1ACP1ENPP2 | |
| SCHEMBL12177324 | 0.89 | PPARG (0.62) | PTPN1ACP1ENPP2 | |
| SCHEMBL12177161 | 0.84 | PPARG (0.64) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177684 | 0.84 | ENPP2 (0.67) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177314 | 0.83 | PTPN1 (0.58) | PTPN1ACP1PTPN2PTPRFPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |