Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | ACP1 | P24666 | 3/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177416 | 0.97 | PTPN1 (0.60) | PIM1PPARGCISD1PTPN1ACP1 | |
| SCHEMBL12177324 | 0.96 | PPARG (0.62) | PIM1PPARGCISD1PTPN1ACP1 | |
| SCHEMBL12177785 | 0.96 | PIM1 (0.56) | PIM1PPARGCISD1PTPN1ACP1 | |
| SCHEMBL12177549 | 0.96 | PPARG (0.64) | PIM1PPARGCISD1PTPN1ACP1 | |
| SCHEMBL12177458 | 0.92 | PTPN1 (0.71) | PTPN1ACP1ENPP2 | |
| SCHEMBL12177161 | 0.92 | PPARG (0.64) | PIM1PPARGCISD1PTPN1ACP1 | |
| SCHEMBL12177396 | 0.89 | ENPP2 (0.68) | PTPN1ACP1AKR1B1ENPP2MAPK1 | |
| SCHEMBL12177684 | 0.89 | ENPP2 (0.67) | PPARGPTPN1ACP1AKR1B1ENPP2 | |
| SCHEMBL12177568 | 0.89 | MAPK1 (0.66) | PPARGPTPN1ACP1ENPP2MAPK1 | |
| SCHEMBL12177385 | 0.85 | ENPP2 (0.71) | PPARGPTPN1ACP1ENPP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |