Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 14/20 | 0.66 |
| ▸ | ACP1 | P24666 | 12/20 | 0.66 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.60 |
| ▸ | PTPRF | P10586 | 2/20 | 0.60 |
| ▸ | PTPRB | P23467 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177458 | 0.94 | PTPN1 (0.71) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL12177416 | 0.90 | PTPN1 (0.60) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL12177290 | 0.89 | ENPP2 (0.74) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL12177353 | 0.89 | PIM1 (0.59) | ENPP2PTPN1ACP1PKMMAPK1 | |
| SCHEMBL12177303 | 0.89 | ENPP2 (0.55) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL12177549 | 0.87 | PPARG (0.64) | ENPP2PTPN1ACP1PTPN2NPSR1 | |
| SCHEMBL12177740 | 0.86 | ENPP2 (0.55) | ENPP2PTPN1ACP1PTPN2PTPRF | |
| SCHEMBL12177324 | 0.85 | PPARG (0.62) | ENPP2PTPN1ACP1MAPK1AKR1B1 | |
| SCHEMBL12177785 | 0.85 | PIM1 (0.56) | ENPP2PTPN1ACP1AKR1B1 | |
| SCHEMBL12177383 | 0.85 | MEN1 (0.67) | ENPP2PTPN1ACP1PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |