Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177367 | 0.95 | MAPK1 (0.49) | ENPP2PPARGALDH1A1PTPN1 | |
| SCHEMBL12177406 | 0.91 | PPARG (0.54) | ENPP2PPARGALDH1A1PTPN1MEN1 | |
| SCHEMBL12177484 | 0.90 | PPARG (0.55) | ENPP2PPARGALDH1A1PTPN1MEN1 | |
| SCHEMBL12177155 | 0.89 | PPARG (0.63) | ENPP2PPARGALDH1A1PTPN1 | |
| SCHEMBL12177690 | 0.88 | PPARG (0.59) | ENPP2PPARGALDH1A1PTPN1MEN1 | |
| SCHEMBL12177385 | 0.87 | ENPP2 (0.71) | ENPP2PPARGPTPN1 | |
| SCHEMBL12177349 | 0.87 | PPARG (0.64) | ENPP2PPARGALDH1A1PTPN1 | |
| SCHEMBL12177303 | 0.85 | ENPP2 (0.55) | ENPP2PTPN1 | |
| SCHEMBL12177549 | 0.84 | PPARG (0.64) | ENPP2PPARGPTPN1HPGDNPSR1 | |
| SCHEMBL12177128 | 0.84 | PTPN1 (0.61) | ENPP2PPARGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |