Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.48 |
| ▸ | ACP1 | P24666 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177366 | 0.90 | ENPP2 (0.54) | PPARGALDH1A1ENPP2MEN1KMT2A | |
| SCHEMBL12177155 | 0.87 | PPARG (0.63) | PPARGALDH1A1ENPP2AKR1B1PTPN1 | |
| SCHEMBL12177160 | 0.87 | PPARG (0.70) | PPARGENPP2AKR1B1CISD1PTPN1 | |
| SCHEMBL12177686 | 0.85 | PPARG (0.56) | PPARGALDH1A1ENPP2AKR1B1MEN1 | |
| SCHEMBL12177303 | 0.85 | ENPP2 (0.55) | ENPP2PTPN1ACP1PTPN2 | |
| SCHEMBL12177367 | 0.84 | MAPK1 (0.49) | PPARGALDH1A1ENPP2PTPN1ACP1 | |
| SCHEMBL12177690 | 0.82 | PPARG (0.59) | PPARGALDH1A1ENPP2MEN1KMT2A | |
| SCHEMBL12177524 | 0.81 | PIK3CG (0.57) | PPARGALDH1A1ENPP2MEN1KMT2A | |
| SCHEMBL12177349 | 0.81 | PPARG (0.64) | PPARGALDH1A1ENPP2AKR1B1PTPN1 | |
| SCHEMBL12177549 | 0.80 | PPARG (0.64) | PPARGENPP2AKR1B1CISD1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |