Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | DUSP26 | Q9BV47 | 2/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177712 | 0.88 | AURKA (0.75) | LMNATDP1AURKAPSMB8 | |
| SCHEMBL12177489 | 0.86 | ALDH1A1 (0.57) | LMNATDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL12177280 | 0.84 | NPC1 (0.66) | TDP1POLBL3MBTL1 | |
| SCHEMBL12177573 | 0.84 | AURKA (0.60) | LMNATDP1DUSP26AURKA | |
| SCHEMBL12177391 | 0.84 | PTPN2 (0.57) | LMNATDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL12177166 | 0.82 | AURKA (0.70) | LMNATDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL12177755 | 0.82 | AURKA (0.60) | LMNATDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL12177685 | 0.82 | AURKA (0.65) | LMNATDP1MEN1ALDH1A1KMT2A | |
| SCHEMBL12177501 | 0.81 | PTPN2 (0.61) | TDP1MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL12177731 | 0.81 | PTPN2 (0.61) | TDP1MEN1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |