Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGAV | P06756 | 2/20 | 0.54 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DUSP26 | Q9BV47 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177580 | 0.90 | MGAM (0.60) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL12177391 | 0.90 | PTPN2 (0.57) | ALDH1A1MEN1POLBMAPTKMT2A | |
| SCHEMBL12177755 | 0.87 | AURKA (0.60) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL12177369 | 0.86 | LMNA (0.62) | ALDH1A1MEN1POLBMAPTKMT2A | |
| SCHEMBL12177783 | 0.84 | MGAM (0.57) | ALDH1A1MEN1MAPTKMT2ATDP1 | |
| SCHEMBL12177288 | 0.83 | TDP1 (0.55) | ALDH1A1POLBMAPTTDP1LMNA | |
| SCHEMBL12177501 | 0.83 | PTPN2 (0.61) | ALDH1A1MEN1POLBMAPTKMT2A | |
| SCHEMBL12177731 | 0.83 | PTPN2 (0.61) | ALDH1A1MEN1POLBMAPTKMT2A | |
| SCHEMBL12177727 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTTDP1LMNA | |
| SCHEMBL12177724 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |