Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.61 |
| ▸ | ACP1 | P24666 | 10/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.59 |
| ▸ | PTPRF | P10586 | 2/20 | 0.59 |
| ▸ | PTPRB | P23467 | 2/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.56 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.54 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177737 | 0.91 | ENPP2 (0.58) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177152 | 0.90 | PPARG (0.60) | PTPN1ACP1PTPN22ENPP2PPARG | |
| SCHEMBL20339633 | 0.89 | PTPN1 (0.71) | PTPN1NLRP3PTPN22DUSP22 | |
| SCHEMBL20339632 | 0.89 | PTPN1 (0.71) | PTPN1NLRP3PTPN22DUSP22 | |
| SCHEMBL12177314 | 0.88 | PTPN1 (0.58) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177720 | 0.88 | PPARG (0.61) | PTPN22ENPP2PPARG | |
| SCHEMBL12177427 | 0.87 | PPARG (0.67) | PTPN22ENPP2PPARG | |
| SCHEMBL12177447 | 0.83 | PTPN22 (0.55) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177128 | 0.83 | PTPN1 (0.61) | PTPN1ACP1PTPN2PTPRFPTPRB | |
| SCHEMBL12177336 | 0.82 | PTPN1 (0.74) | PTPN1ACP1PTPN2PTPRFPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |