Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | ACP1 | P24666 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | PTPRF | P10586 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177157 | 0.87 | ALDH1A1 (0.52) | PTPN22ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177376 | 0.85 | ALDH1A1 (0.50) | PTPN22ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177339 | 0.84 | PTPN1 (0.61) | PTPN22ALDH1A1PTPN1ACP1GAA | |
| SCHEMBL12177374 | 0.83 | PTPN1 (0.61) | PTPN22PTPN1ACP1ENPP2NLRP3 | |
| SCHEMBL12177132 | 0.82 | ALDH1A1 (0.50) | PTPN22ALDH1A1PTPN1ACP1KDR | |
| SCHEMBL12177514 | 0.80 | PTPN22 (0.50) | PTPN22ALDH1A1SMN1; SMN2 | |
| SCHEMBL12177314 | 0.79 | PTPN1 (0.58) | PTPN22PTPN1ACP1ENPP2PTPRF | |
| SCHEMBL12177763 | 0.78 | ENPP2 (0.69) | PTPN22ENPP2 | |
| SCHEMBL12177762 | 0.77 | CISD1 (0.49) | PTPN22ALDH1A1PTPN1GAASMN1; SMN2 | |
| SCHEMBL12177341 | 0.76 | AKR1B1 (0.58) | ALDH1A1PTPN1ACP1ENPP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |