Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 6/20 | 0.47 |
| ▸ | PRF1 | P14222 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177157 | 0.88 | ALDH1A1 (0.52) | ALDH1A1TDP1PTPN22PPARGGAA | |
| SCHEMBL12177447 | 0.85 | PTPN22 (0.55) | ALDH1A1PTPN22GAASMN1; SMN2 | |
| SCHEMBL12177456 | 0.83 | TDP1 (0.65) | ALDH1A1TDP1L3MBTL1PPARGGAA | |
| SCHEMBL12177720 | 0.82 | PPARG (0.61) | ALDH1A1PTPN22PPARG | |
| SCHEMBL12177578 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1PPARGGAA | |
| SCHEMBL12177762 | 0.79 | CISD1 (0.49) | ALDH1A1PTPN22PPARGGAASMN1; SMN2 | |
| SCHEMBL12177553 | 0.79 | PPARG (0.54) | ALDH1A1TDP1L3MBTL1PPARGGAA | |
| SCHEMBL12177709 | 0.79 | PRF1 (0.48) | TDP1PTPN22PRF1PPARGGAA | |
| SCHEMBL12177723 | 0.78 | PPARG (0.55) | ALDH1A1TDP1L3MBTL1PTPN22PPARG | |
| SCHEMBL12177595 | 0.77 | KMT2A (0.64) | ALDH1A1TDP1L3MBTL1PTPN22SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |