Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177581 | 0.91 | ALDH1A1 (0.58) | PPARGALDH1A1GAASMN1; SMN2AKR1B1 | |
| SCHEMBL12177456 | 0.88 | TDP1 (0.65) | PPARGALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL12177286 | 0.84 | PPARG (0.76) | PPARGALDH1A1CA9AKR1B1PTPN1 | |
| SCHEMBL12177363 | 0.82 | CISD1 (0.63) | PPARGALDH1A1GAASMN1; SMN2AKR1B1 | |
| SCHEMBL12177578 | 0.81 | ALDH1A1 (0.53) | PPARGALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL12177341 | 0.79 | AKR1B1 (0.58) | PPARGALDH1A1GAASMN1; SMN2AKR1B1 | |
| SCHEMBL12177136 | 0.79 | CISD1 (0.56) | PPARGALDH1A1GAASMN1; SMN2CA9 | |
| SCHEMBL12177376 | 0.79 | ALDH1A1 (0.50) | PPARGALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL12177324 | 0.79 | PPARG (0.62) | PPARGALDH1A1TDP1L3MBTL1AKR1B1 | |
| SCHEMBL12177475 | 0.77 | PPARG (0.73) | PPARGALDH1A1AKR1B1MAPK1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |