Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.52 |
| ▸ | ITGAM | P11215 | 3/20 | 0.52 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.51 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177565 | 0.88 | MAP3K5 (0.62) | MEN1KMT2APOLBL3MBTL1ITGB2 | |
| SCHEMBL12177493 | 0.85 | MEN1 (0.59) | PIK3CGMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL12177524 | 0.85 | PIK3CG (0.57) | PIK3CGMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL3134591 | 0.84 | MEN1 (0.63) | PIK3CGMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL3134579 | 0.84 | MEN1 (0.63) | PIK3CGMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL3134585 | 0.84 | MEN1 (0.63) | PIK3CGMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL12177523 | 0.83 | PIK3CG (0.65) | PIK3CGMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL12177363 | 0.83 | CISD1 (0.63) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL12177496 | 0.82 | MEN1 (0.69) | PIK3CGMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL12177136 | 0.82 | CISD1 (0.56) | SMN1; SMN2ALDH1A1MAPK1CISD1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |