Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177363 | 0.93 | CISD1 (0.63) | CISD1AKR1B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177161 | 0.84 | PPARG (0.64) | CISD1AKR1B1ALDH1A1PPARGMAPK1 | |
| SCHEMBL12177160 | 0.84 | PPARG (0.70) | CISD1AKR1B1PPARGPTPN1 | |
| SCHEMBL12177762 | 0.83 | CISD1 (0.49) | CISD1AKR1B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177452 | 0.82 | PIK3CG (0.58) | CISD1AKR1B1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL12177341 | 0.81 | AKR1B1 (0.58) | AKR1B1ALDH1A1GAASMN1; SMN2PPARG | |
| SCHEMBL12177581 | 0.81 | ALDH1A1 (0.58) | AKR1B1ALDH1A1GAASMN1; SMN2PPARG | |
| SCHEMBL12177156 | 0.81 | ALDH1A1 (0.61) | CISD1AKR1B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177553 | 0.79 | PPARG (0.54) | CISD1AKR1B1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12177456 | 0.78 | TDP1 (0.65) | AKR1B1ALDH1A1GAASMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |