Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.47 |
| ▸ | ITGAM | P11215 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177526 | 0.86 | MAP3K5 (0.60) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL12177545 | 0.84 | PSMB8 (0.66) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL12177452 | 0.83 | PIK3CG (0.58) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL12177733 | 0.83 | RAB9A (0.77) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL12177524 | 0.83 | PIK3CG (0.57) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL12177493 | 0.83 | MEN1 (0.59) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL12177546 | 0.82 | PSMB8 (0.57) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL12177547 | 0.82 | PSMB8 (0.56) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL12177382 | 0.81 | POLB (0.66) | PIK3CGPOLBRAB9AALDH1A1MAPT | |
| SCHEMBL3135568 | 0.80 | MAP3K5 (0.64) | PIK3CGPOLBRAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |