Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177202 | 0.88 | ALDH1A1 (0.60) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL3897032 | 0.88 | POLB (0.78) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL3897031 | 0.88 | POLB (0.78) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL7858419 | 0.88 | POLB (0.78) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL12177733 | 0.87 | RAB9A (0.77) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL12177526 | 0.85 | MAP3K5 (0.60) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL12177594 | 0.83 | PSMB8 (0.70) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL5145149 | 0.81 | KMT2A (0.68) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL5145153 | 0.81 | KMT2A (0.68) | ALDH1A1POLBMAPTRAB9ALMNA | |
| SCHEMBL12177593 | 0.81 | PSMB8 (0.78) | ALDH1A1POLBMAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |