Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 8/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177546 | 0.93 | PSMB8 (0.57) | PSMB8PIK3CGALDH1A1POLBMAPT | |
| SCHEMBL12177547 | 0.92 | PSMB8 (0.56) | PSMB8PIK3CGALDH1A1POLBMAPT | |
| SCHEMBL12177213 | 0.89 | PSMB8 (0.75) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177782 | 0.88 | PSMB8 (0.82) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177564 | 0.84 | PSMB8 (0.67) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177523 | 0.84 | PIK3CG (0.65) | PSMB8PIK3CGALDH1A1POLBMAPT | |
| SCHEMBL12177463 | 0.83 | TDP1 (0.58) | ALDH1A1POLBMAPTLMNATDP1 | |
| SCHEMBL12177573 | 0.82 | AURKA (0.60) | LMNATDP1AURKA | |
| SCHEMBL12177187 | 0.82 | PSMB8 (0.80) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177746 | 0.82 | PSMB8 (0.73) | PSMB8ALDH1A1POLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |