Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 4/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | POLB | P06746 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177546 | 0.92 | PSMB8 (0.57) | PSMB8PIK3CGTDP1MEN1KMT2A | |
| SCHEMBL12177545 | 0.92 | PSMB8 (0.66) | PSMB8PIK3CGTDP1MEN1KMT2A | |
| SCHEMBL12177333 | 0.89 | PSMB8 (0.62) | PSMB8TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL12177594 | 0.86 | PSMB8 (0.70) | PSMB8TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL12177564 | 0.84 | PSMB8 (0.67) | PSMB8TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL12177593 | 0.83 | PSMB8 (0.78) | PSMB8TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL12177522 | 0.83 | ALDH1A1 (0.50) | TDP1ALDH1A1MAPTPOLBNPSR1 | |
| SCHEMBL12177429 | 0.82 | PSMB8 (0.65) | PSMB8TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL12177523 | 0.82 | PIK3CG (0.65) | PSMB8PIK3CGTDP1MEN1KMT2A | |
| SCHEMBL14426563 | 0.81 | PSMB8 (0.75) | PSMB8TDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |