Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177767 | 0.94 | PPARG (0.54) | PPARGAKR1B1PTPN22CISD1 | |
| SCHEMBL12177143 | 0.91 | PPARG (0.59) | PPARGENPP2ALDH1A1 | |
| SCHEMBL12177152 | 0.88 | PPARG (0.60) | PPARGENPP2PTPN22ALDH1A1 | |
| SCHEMBL12177531 | 0.85 | PPARG (0.54) | PPARGENPP2PTPN22ALDH1A1 | |
| SCHEMBL12177740 | 0.85 | ENPP2 (0.55) | PPARGENPP2PTPN22 | |
| SCHEMBL12177762 | 0.85 | CISD1 (0.49) | PPARGAKR1B1PTPN22ALDH1A1CISD1 | |
| SCHEMBL12177484 | 0.85 | PPARG (0.55) | PPARGENPP2AKR1B1ALDH1A1MEN1 | |
| SCHEMBL12177160 | 0.84 | PPARG (0.70) | PPARGENPP2AKR1B1CISD1 | |
| SCHEMBL12177427 | 0.83 | PPARG (0.67) | PPARGENPP2PTPN22ALDH1A1MEN1 | |
| SCHEMBL12177764 | 0.83 | PPARG (0.44) | PPARGAKR1B1PTPN22ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |