Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.70 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.57 |
| ▸ | ACP1 | P24666 | 4/20 | 0.57 |
| ▸ | PTPRF | P10586 | 2/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.57 |
| ▸ | PTPRB | P23467 | 2/20 | 0.57 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177161 | 0.94 | PPARG (0.64) | PPARGENPP2AKR1B1PTPN1ACP1 | |
| SCHEMBL12177385 | 0.90 | ENPP2 (0.71) | PPARGENPP2PTPN1ACP1PTPRF | |
| SCHEMBL12177549 | 0.90 | PPARG (0.64) | PPARGENPP2AKR1B1PTPN1ACP1 | |
| SCHEMBL12177684 | 0.89 | ENPP2 (0.67) | PPARGENPP2AKR1B1PTPN1ACP1 | |
| SCHEMBL12177758 | 0.87 | PPARG (0.82) | PPARGENPP2AKR1B1PTPN1ACP1 | |
| SCHEMBL12177484 | 0.87 | PPARG (0.55) | PPARGENPP2AKR1B1PTPN1ACP1 | |
| SCHEMBL12177416 | 0.86 | PTPN1 (0.60) | PPARGENPP2AKR1B1PTPN1ACP1 | |
| SCHEMBL12177353 | 0.85 | PIM1 (0.59) | PPARGENPP2AKR1B1PTPN1ACP1 | |
| SCHEMBL12177568 | 0.84 | MAPK1 (0.66) | PPARGENPP2PTPN1ACP1PTPRF | |
| SCHEMBL12177136 | 0.84 | CISD1 (0.56) | PPARGAKR1B1PTPN1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |