Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | MGAM | O43451 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177463 | 0.93 | TDP1 (0.58) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177724 | 0.92 | ALDH1A1 (0.59) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177727 | 0.92 | ALDH1A1 (0.59) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177732 | 0.91 | MGAM (0.57) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177552 | 0.91 | MGAM (0.57) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177373 | 0.91 | MGAM (0.61) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177501 | 0.91 | PTPN2 (0.61) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177731 | 0.91 | PTPN2 (0.61) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177573 | 0.90 | AURKA (0.60) | CA9MGAMCA12CA1CA2 | |
| SCHEMBL12177682 | 0.89 | CA9 (0.70) | CA9MGAMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |