Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ACP1 | P24666 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177724 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TDP1MAPTNPSR1POLB | |
| SCHEMBL12177288 | 0.93 | TDP1 (0.55) | ALDH1A1TDP1MAPTNPSR1POLB | |
| SCHEMBL12177688 | 0.92 | CA9 (0.57) | ALDH1A1TDP1MAPTNPSR1POLB | |
| SCHEMBL12177552 | 0.91 | MGAM (0.57) | ALDH1A1TDP1MAPTNPSR1POLB | |
| SCHEMBL12177732 | 0.91 | MGAM (0.57) | ALDH1A1TDP1MAPTNPSR1POLB | |
| SCHEMBL12177373 | 0.91 | MGAM (0.61) | ALDH1A1TDP1MAPTNPSR1POLB | |
| SCHEMBL12177580 | 0.90 | MGAM (0.60) | ALDH1A1TDP1MAPTMGAMCA12 | |
| SCHEMBL12177755 | 0.89 | AURKA (0.60) | ALDH1A1TDP1MAPTMGAMCA12 | |
| SCHEMBL12177731 | 0.89 | PTPN2 (0.61) | ALDH1A1TDP1MAPTNPSR1POLB | |
| SCHEMBL12177501 | 0.89 | PTPN2 (0.61) | ALDH1A1TDP1MAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |