Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177979 | 0.92 | MAPT (0.43) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL2593020 | 0.83 | MAPT (0.46) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL2588599 | 0.74 | MAPT (0.48) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL493454 | 0.69 | CHRNB2 (0.62) | SMN1; SMN2ALDH1A1LMNAHTTHPGD | |
| SCHEMBL3109609 | 0.68 | MAPT (0.67) | MAPTSMN1; SMN2ALDH1A1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL2591580 | 0.68 | CHRNB2 (0.60) | SMN1; SMN2ALDH1A1LMNAHTTHPGD | |
| Ammonia Solution, Strong SCHEMBL1764234 | 0.68 | CHRNB2 (0.60) | SMN1; SMN2ALDH1A1LMNAHTTHPGD | |
| SCHEMBL2591565 | 0.67 | ACACB (0.53) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14718387 | 0.67 | QDPR (0.36) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13178107 | 0.67 | ALDH1A1 (0.53) | MAPTSMN1; SMN2ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140160-A1 | BICYCLIC HETEROARYL COMPOUNDS AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-11-10 | — | — | WO | disclosed |