Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.61 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL30076353 | 1.00 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL121844 | 1.00 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL17352178 | 0.98 | GSR (0.59) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL587923 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL896278 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL25283016 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL3427044 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL7197544 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL1281705 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| Lysine SCHEMBL896279 | 0.95 | GSR (0.61) | GSRRNPEPGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4529458-A1 | NUTRACEUTICAL OR PHARMACEUTICAL COMPOSITION FOR MALE INFERTILITY | Neilos S.r.l. (IT) | 2025-04-02 | — | — | EP | claimed |
| CN-119613449-A | Method for extracting glyphosate from glyphosate mother liquor | 湖北泰盛化工有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119424743-A | Bone repair implant based on cold junction resin calcium glycerophosphate composite gel and preparation method thereof | 中鼎凯瑞科技成都有限公司 | 2025-02-14 | — | — | CN | claimed |
| US-11850294-B2 | Buffered microencapsulated compositions and methods | PREMIER DENTAL PRODUCTS COMPANY (US) | 2023-12-26 | — | — | US | claimed |
| WO-2023228062-A1 | NUTRACEUTICAL OR PHARMACEUTICAL COMPOSITION FOR MALE INFERTILITY | Neilos S.r.l. (IT) | 2023-11-30 | — | — | WO | claimed |
| CN-113973789-B | Environment-friendly composite bait and preparation process thereof | 武汉天元千川渔具有限公司 | 2023-02-03 | — | — | CN | claimed |
| US-20220079849-A1 | BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS | FIDELITY DIRECT LENDING LLC, AS ADMINISTRATIVE AGENT | 2022-03-17 | — | — | US | claimed |
| CN-113973789-A | Environment-friendly composite bait and preparation process thereof | 武汉天元千川渔具有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-112675160-A | Amino acid mineral salt trace element composition and preparation method thereof | 河北力维素科技有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-111557451-A | Novel composite short peptide assembly | 厦门肽王基因科技有限公司 | 2020-08-21 | — | — | CN | claimed |
| CN-101058782-B | Sports beer | JINLAI MIAO | 2010-12-22 | — | — | CN | claimed |
| CN-101913237-A | Manufacturing method of high-temperature resistant and corrosion-resistant polyphenyl thioether composite tube | XUN CHEN | 2010-12-15 | — | — | CN | claimed |
| WO-2010117370-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | claimed |
| US-20090269399-A1 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF | CYPRESS PHARMACEUTICAL, INC. (US) | 2009-10-29 | — | — | US | claimed |
| CN-101058782-A | Sports beer | MIAO JINLAI (CN) | 2007-10-24 | — | — | CN | claimed |
| CN-1943594-A | Oral disintegrating tablet of lysine calcium mono hydrogen phosphate | ZHANG GUOQING (CN) | 2007-04-11 | — | — | CN | claimed |
| EP-1286667-B1 | COMPOSITION FOR THE TREATMENT AND/OR THE PREVENTION OF OSTEOPOROSIS AND/OR INFLAMMATORY JOINT DISEASES | MERCK PATENT GMBH (DE) | 2006-06-14 | — | — | EP | claimed |
| CN-1546015-A | Composition containing amino acid calcium and soy isoflavone | 北京邦法姆生物医药科技有限公司 | 2004-11-17 | — | — | CN | claimed |
| EP-0871428-B1 | PREPARATION USED IN DENTAL CARE | NEOCARE OY (FI) | 2004-01-28 | — | — | EP | claimed |
| EP-0491638-A2 | Method of making granulated L-lysine | ARCHER-DANIELS-MIDLAND COMPANY (US) | 1992-06-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11850294-B2 | Buffered microencapsulated compositions and methods | CHMP4B, LIPA, APOB | GSR 1160/4885RNPEP 488/4885GNAI3 4003/4885 |
| US-20220079849-A1 | BUFFERED MICROENCAPSULATED COMPOSITIONS AND METHODS | CHMP4B, LIPA, APOB | GSR 1160/4885RNPEP 488/4885GNAI3 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.