Cyproximide

Cyproximide

SCHEMBL121879

O=C1NC(=O)C2(c3ccc(Cl)cc3)CC12

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.70
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
KDM1A O60341 2/20 0.39
LIG1 P18858 1/20 0.37
KMT2A Q03164 2/20 0.36
MAPK1 P28482 1/20 0.36
CXCR3 P49682 1/20 0.35
CRBN Q96SW2 2/20 0.35
DDB1 Q16531 1/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
RCOR1 Q9UKL0 1/20 0.34
DRD2 P14416 1/20 0.33
TP53 P04637 1/20 0.33
MDM2 Q00987 1/20 0.33
HTR6 P50406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14520901 0.84 CYP19A1 (0.72) CYP19A1MAOAMAOBCXCR3CRBN
SCHEMBL4556388 0.84 CYP19A1 (0.72) CYP19A1MAOAMAOBCXCR3CRBN
SCHEMBL4759593 0.82 CYP19A1 (0.70) CYP19A1KDM1ALIG1CXCR3CRBN
SCHEMBL10530071 0.82 CYP19A1 (1.00) CYP19A1
SCHEMBL22623727 0.82 CYP19A1 (1.00) CYP19A1
SCHEMBL8245665 0.82 CYP19A1 (0.70) CYP19A1KDM1ALIG1CXCR3CRBN
SCHEMBL10530941 0.82 CYP19A1 (1.00) CYP19A1
SCHEMBL13201868 0.82 CYP19A1 (0.70) CYP19A1KDM1ALIG1CXCR3CRBN
SCHEMBL2054565 0.81 CYP19A1 (0.69) CYP19A1MAOAMAOBKDM1AKMT2A
SCHEMBL1552771 0.81 CYP19A1 (0.69) CYP19A1MAOAMAOBKDM1AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
WO-1997041878-A1 TREATMENT OF MOOD DISORDERS WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO., INC. (US) 1997-11-13 WO claimed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
US-20250339367-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
US-4131611-A ANXIOLYTIC, ANALGESIC AMERICAN CYANAMID COMPANY (US) 1978-12-26 US disclosed
US-4118393-A Phenyl azabicyclohexanones AMERICAN CYANAMID COMPANY (US) 1978-10-03 US disclosed
US-4088652-A Acylazabicyclohexanes AMERICAN CYANAMID COMPANY (US) 1978-05-09 US disclosed
US-3892772-A Isomer of 1-(p-chlorophenyl)-1,2-cyclopropanedicarboximide and method of use AMERICAN CYANAMID CO 1975-07-01 US disclosed
US-3892772-A Isomer of 1-(p-chlorophenyl)-1,2-cyclopropanedicarboximide and method of use AMERICAN CYANAMID CO 1975-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A CYP19A1 1744/4885MAOA 1528/4885MAOB 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.