Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568142 | 0.69 | — | — | |
| SCHEMBL13897149 | 0.64 | LMNA (0.43) | CES2CES1TSHRALDH1A1HSD17B10 | |
| SCHEMBL1035354 | 0.63 | ESR1 (0.56) | CES2CES1TSHRALDH1A1HSD17B10 | |
| SCHEMBL10893693 | 0.63 | CES1 (0.47) | CES2CES1TSHRALDH1A1HSD17B10 | |
| SCHEMBL1800935 | 0.63 | — | — | |
| SCHEMBL7541566 | 0.63 | — | — | |
| SCHEMBL11844374 | 0.63 | ESR1 (0.56) | CES2CES1TSHRALDH1A1HSD17B10 | |
| SCHEMBL10877617 | 0.63 | CES2 (0.52) | CES2CES1TSHRALDH1A1HSD17B10 | |
| SCHEMBL1567792 | 0.63 | CES1 (0.47) | CES2CES1TSHRALDH1A1HSD17B10 | |
| SCHEMBL38015 | 0.63 | CES1 (0.52) | CES2CES1TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2372804-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND COMPOUND | Idemitsu Kosan Co., Ltd. (JP) | 2011-10-05 | — | — | EP | disclosed |