Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tramazoline SCHEMBL121943 | 0.99 | LMNA (0.68) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Tramazoline SCHEMBL29362958 | 0.99 | LMNA (0.68) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Tramazoline SCHEMBL8378445 | 0.97 | LMNA (0.67) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Indanazoline SCHEMBL151815 | 0.97 | LMNA (0.66) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Indanazoline SCHEMBL1650054 | 0.96 | LMNA (0.65) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Indanazoline SCHEMBL3500123 | 0.96 | LMNA (0.65) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Tramazoline SCHEMBL4760046 | 0.88 | LMNA (0.63) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Indanazoline SCHEMBL11372740 | 0.87 | LMNA (0.66) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Tramazoline SCHEMBL28086399 | 0.81 | TAAR1 (0.61) | LMNACYP2D6CYP2C19ADRA2AADRA2B | |
| Indanazoline SCHEMBL3064466 | 0.81 | ADRA1A (0.67) | LMNACYP2D6CYP2C19ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4548 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122075410-A | Dry powder composition for intranasal delivery | — | 2026-05-26 | — | — | CN | claimed |
| US-20260108531-A1 | Methods of Treating Hypogonadism with Transnasal Testosterone Bio-adhesive Gel Formulations in Males with Allergic Rhinitis and Methods for Preventing an Allergic Rhinitis Event | ACERUS BIOPHARMA INC (CA) | 2026-04-23 | — | — | US | claimed |
| US-12605345-B2 | Transdermal drug delivery system | BioPhysics Pharma, Inc. (US) | 2026-04-21 | — | — | US | claimed |
| CN-120114603-A | Compound pharmaceutical composition for treating presbyopia as well as preparation method, application and preparation thereof | 立生医药(苏州)有限公司 | 2025-06-10 | — | — | CN | claimed |
| EP-3359134-B1 | COMPOSITIONS AND COMPOSITIONS FOR USE IN ON-DEMAND HIGH-EFFICIENCY TRIGGERABLE ANESTHESIA | CHILDRENS MEDICAL CT CORP (US) | 2025-04-09 | — | — | EP | claimed |
| CN-119700672-A | An eye spray composition for relieving ptosis and redeye | 立生医药(苏州)有限公司 | 2025-03-28 | — | — | CN | claimed |
| US-20250049761-A1 | COMPOSITIONS AND METHODS FOR TREATING PRESBYOPIA, MILD HYPEROPIA, AND IRREGULAR ASTIGMATISM | ALLERGAN, INC. | 2025-02-13 | — | — | US | claimed |
| US-20240316063-A1 | METHODS OF TREATING HYPOGONADISM WITH TRANSNASAL TESTOSTERONE BIO-ADHESIVE GEL FORMULATIONS IN MALE WITH ALLERGIC RHINITIS, AND METHODS FOR PREVENTING AN ALLERGIC RHINITIS EVENT | ACERUS BIOPHARMA INC (CA) | 2024-09-26 | — | — | US | claimed |
| EP-3756665-B1 | INTERVAL THERAPY FOR THE TREATMENT OF EYE DISEASES | UNIV RAMOT (IL) | 2024-08-14 | — | — | EP | claimed |
| US-20240108588-A1 | Transdermal Drug Delivery System | Masiz, John J. (US) | 2024-04-04 | — | — | US | claimed |
| WO-1993024149-A1 | PHARMACEUTICAL POWDER COMPOSITION CONTAINING NON-IONIC CELLULOSE ETHER DERIVATIVE AND A CHITIN-DERIVED POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1993-12-09 | — | — | WO | claimed |
| EP-0571671-A1 | A Pharmaceutical composition in powder form | THE PROCTER & GAMBLE COMPANY (US) | 1993-12-01 | — | — | EP | claimed |
| EP-0550921-A1 | Pharmaceutical composition for ophthalmic use comprising a nonsteroidal anti-inflammatory and a decongestant drug | ZAMBON GROUP S.p.A. (IT) | 1993-07-14 | — | — | EP | claimed |
| WO-1992014453-A1 | COMPOSITIONS AND METHODS OF TREATMENT OF SYMPATHETICALLY MAINTAINED PAIN | ARC 1, INC. (US) | 1992-09-03 | — | — | WO | claimed |
| EP-0170193-B1 | FEEDSTUFF ADDITIVE FOR THE GROWTH PROMOTING OF AGRICULTURAL USEFUL ANIMALS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1991-12-27 | — | — | EP | claimed |
| EP-0448299-A2 | Composition for increased skin concentration of active agents by iontophoresis | Becton, Dickinson and Company (US) | 1991-09-25 | — | — | EP | claimed |
| US-4853402-A | 2-SUBSTITUTED-2-IMIDAZOLINES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1989-08-01 | — | — | US | claimed |
| EP-0086428-B1 | ANTIDIARRHOEA VETERINARY COMPOSITION, ITS PRODUCTION AND ORAL DOSER CONTAINING IT | BEECHAM GROUP PLC (GB) | 1987-07-29 | — | — | EP | claimed |
| EP-0170193-A2 | Feedstuff additive for the growth promoting of agricultural useful animals | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1986-02-05 | — | — | EP | claimed |
| EP-0025269-B1 | ANTI-DIARRHOEA VETERINARY COMPOSITION | BEECHAM GROUP PLC (GB) | 1985-11-13 | — | — | EP | claimed |