Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 15/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 15/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12195935 | 0.93 | OPRD1 (0.59) | OPRD1OPRM1OPRK1 | |
| SCHEMBL30301310 | 0.90 | OPRM1 (0.74) | OPRD1OPRM1OPRK1 | |
| SCHEMBL16807428 | 0.89 | OPRD1 (0.64) | OPRD1OPRM1OPRK1 | |
| SCHEMBL16807432 | 0.89 | OPRD1 (0.64) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27855934 | 0.85 | OPRM1 (0.72) | OPRD1OPRM1OPRK1 | |
| SCHEMBL12195913 | 0.85 | OPRM1 (0.65) | OPRD1OPRM1OPRK1 | |
| SCHEMBL15449784 | 0.84 | OPRD1 (0.67) | OPRD1OPRM1OPRK1 | |
| SCHEMBL22959885 | 0.83 | OPRD1 (0.77) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29894293 | 0.83 | OPRD1 (0.77) | OPRD1OPRM1OPRK1 | |
| Diacetylmorphine SCHEMBL30301301 | 0.82 | OPRD1 (0.74) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150165052-A1 | Hybrid Opioid Compounds and Compositions | QRXPHARMA LTD (AU) | 2015-06-18 | — | — | US | disclosed |
| US-8461171-B2 | Hybrid opioid compounds and compositions | QRxPharma Ltd. (AU) | 2013-06-11 | — | — | US | disclosed |
| US-20110245287-A1 | Hybrid Opioid Compounds and Compositions | HOLADAY JOHN W | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150165052-A1 | Hybrid Opioid Compounds and Compositions | OPRM1, OPRK1, OPRL1 | OPRD1 4/4885OPRM1 1/4885OPRK1 2/4885 |
| US-20110245287-A1 | Hybrid Opioid Compounds and Compositions | OPRM1, OPRK1, OPRL1 | OPRD1 4/4885OPRM1 1/4885OPRK1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.