⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194495 | 1.00 | — | — | |
| SCHEMBL276837 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7409622 | 0.98 | CA2 (0.56) | — | |
| SCHEMBL1827755 | 0.93 | CA1 (0.61) | — | |
| SCHEMBL1827758 | 0.93 | CA1 (0.61) | — | |
| SCHEMBL122044 | 0.93 | CA1 (0.61) | — | |
| Formic Acid SCHEMBL29184482 | 0.91 | CA1 (0.50) | — | |
| SCHEMBL18229264 | 0.91 | CA1 (0.50) | — | |
| SCHEMBL23857835 | 0.91 | CA1 (0.59) | — | |
| SCHEMBL10866301 | 0.91 | CA1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030888-B2 | Himastatin derivatives, and processes of preparation thereof, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-09 | — | — | US | disclosed |
| US-20220289750-A1 | HIMASTATIN DERIVATIVES, AND PROCESSES OF PREPARATION THEREOF, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2022-09-15 | — | — | US | disclosed |
| EP-2371366-A1 | Heterocyclo inhibitors of potassium channel function | Bristol-Myers Squibb Company (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2008106225-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |