⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12196153 | 1.00 | — | — | |
| SCHEMBL8194495 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL7409622 | 0.98 | CA2 (0.56) | — | |
| SCHEMBL1827755 | 0.93 | CA1 (0.61) | — | |
| SCHEMBL1827758 | 0.93 | CA1 (0.61) | — | |
| SCHEMBL122044 | 0.93 | CA1 (0.61) | — | |
| Formic Acid SCHEMBL29184482 | 0.91 | CA1 (0.50) | — | |
| SCHEMBL18229264 | 0.91 | CA1 (0.50) | — | |
| SCHEMBL23857835 | 0.91 | CA1 (0.59) | — | |
| SCHEMBL10866301 | 0.91 | CA1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 591 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165070-A | Salt and crystal form of 3CL protease small molecule inhibitor, and preparation methods and applications thereof | 北京华益健康药物研究中心 | 2024-06-11 | — | — | CN | claimed |
| CN-114681443-B | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2024-05-10 | — | — | CN | claimed |
| CN-117979991-A | Methods for treating, ameliorating or preventing infections using drug and vaccination combination therapy | 拓比利亚欧斯特有限公司(ACN 652 771 670) | 2024-05-03 | — | — | CN | claimed |
| CN-117858867-A | SARS-COV-2 MPRO inhibitor compounds | 赫普泰雅治疗有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | claimed |
| EP-4337179-A1 | METHODS FOR TREATING, AMELIORATING OR PREVENTING INFECTIONS USING DRUG AND VACCINATION COMBINATION TREATMENT | Topelia Aust Limited (ACN 652 771 670) (AU) | 2024-03-20 | — | — | EP | claimed |
| EP-4313305-A1 | SARS-COV-2 MPRO INHIBITOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2024-02-07 | — | — | EP | claimed |
| CN-116789648-A | Nitrile-containing antiviral compounds | 辉瑞大药厂 | 2023-09-22 | — | — | CN | claimed |
| CN-116600698-A | Computerized decision support tool and medical device for respiratory condition monitoring and care | 辉瑞公司 | 2023-08-15 | — | — | CN | claimed |
| CN-111601798-B | Bisamide sarcomere activating compounds and uses thereof | 美国安进公司 | 2023-08-11 | — | — | CN | claimed |
| CN-102573879-A | Cathepsin C inhibitors | GLAXO GROUP LTD | 2012-07-11 | — | — | CN | claimed |
| CN-101374823-A | Organic compounds | NOVARTIS AG (CH) | 2009-02-25 | — | — | CN | claimed |
| CN-100427477-C | Process of synthesizing cyclic carbonate by epoxy compound with carbon dioxide reaction | NINGBO WANHUA POLYURETHANE CO (CN) | 2008-10-22 | — | — | CN | claimed |
| CN-101014328-A | Novel biaromatic compounds which activate receptors of PPAR type and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-08-08 | — | — | CN | claimed |
| CN-100999514-A | Process of synthesizing cyclic carbonate by epoxy compound with carbon dioxide reaction | NINGBO WANHUA POLYURETHANE CO (CN) | 2007-07-18 | — | — | CN | claimed |
| US-20030049807-A1 | Micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | INSTITUTO BIOCHIMICO ITALIANO GIOVANNI LOREZINI S.P.A. (IT) | 2003-03-13 | — | — | US | claimed |
| EP-1291435-A2 | A micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) | 2003-03-12 | — | — | EP | claimed |
| CN-1197452-A | Azetidinone derivatives for treatment of atherosclerosis | SMITHKLINE BEECHAM PLC (GB) | 1998-10-28 | — | — | CN | claimed |
| CN-1071434-A | RETROVIRAL PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 1993-04-28 | — | — | CN | claimed |
| EP-0383635-A2 | Peptides having renin inhibitory activity their preparation and use | Sankyo Company Limited (JP) | 1990-08-22 | — | — | EP | claimed |