SCHEMBL12196885

SCHEMBL12196885

C=C(C)C(=O)OCCOc1ccc(OC(=O)c2cc(N)cc(N)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
APEX1 P27695 1/20 0.51
HTT P42858 1/20 0.51
LMNA P02545 6/20 0.42
NPC1 O15118 4/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
NFKB1 P19838 4/20 0.41
NFKB2 Q00653 4/20 0.41
RELA Q04206 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
TSHR P16473 1/20 0.41
PRSS1 P07477 1/20 0.40
ACR P10323 1/20 0.40
MAPT P10636 4/20 0.39
KMT2A Q03164 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18477586 0.89 TDP1 (0.41) POLBTDP1APEX1HTTLMNA
SCHEMBL14627829 0.85 POLB (0.52) POLBTDP1APEX1HTTLMNA
SCHEMBL12196752 0.84 TDP1 (0.59) POLBTDP1APEX1HTTLMNA
SCHEMBL14945506 0.84 ELANE (0.53) TDP1LMNACYP1A2CYP2C9CYP2C19
SCHEMBL12196883 0.84 POLB (0.49) POLBTDP1APEX1HTTNPC1
SCHEMBL19651328 0.83 POLB (0.58) POLBTDP1APEX1HTTLMNA
SCHEMBL10007293 0.83 MAPT (0.46) TDP1LMNASMN1; SMN2MAPTKMT2A
SCHEMBL22354424 0.83 MAPT (0.46) TDP1LMNASMN1; SMN2MAPTKMT2A
SCHEMBL11662637 0.82 TDP1 (0.58) POLBTDP1APEX1HTTLMNA
SCHEMBL353837 0.82 THRB (0.46) POLBTDP1APEX1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9723769-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-01 US disclosed
US-9723769-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-08-01 US disclosed
US-9081237-B2 Pixel electrode panel, a liquid crystal display panel assembly and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-9081237-B2 Pixel electrode panel, a liquid crystal display panel assembly and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-9057917-B2 Pixel electrode panel, a liquid crystal display panel assembly and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-16 US disclosed
US-9057917-B2 Pixel electrode panel, a liquid crystal display panel assembly and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-16 US disclosed
US-20150163968-A1 LIQUID CRYSTAL DISPLAY DEVICE, ALIGNMENT FILM, AND METHODS FOR MANUFACTURING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-06-11 US disclosed
US-20150163968-A1 LIQUID CRYSTAL DISPLAY DEVICE, ALIGNMENT FILM, AND METHODS FOR MANUFACTURING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2015-06-11 US disclosed
US-8962106-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-24 US disclosed
US-8962106-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-02-24 US disclosed
US-8865274-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US disclosed
US-8865274-B2 Liquid crystal display device, alignment film, and methods for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US disclosed
US-20120249940-A1 LIQUID CRYSTAL DISPLAY DEVICE, ALIGNMENT FILM, AND METHODS FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-04 US disclosed
US-20120249940-A1 LIQUID CRYSTAL DISPLAY DEVICE, ALIGNMENT FILM, AND METHODS FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-04 US disclosed
US-20110242443-A1 PIXEL ELECTRODE PANEL, A LIQUID CRYSTAL DISPLAY PANEL ASSEMBLY AND METHODS FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-10-06 US disclosed
US-20110242468-A1 PIXEL ELECTRODE PANEL, A LIQUID CRYSTAL DISPLAY PANEL ASSEMBLY AND METHODS FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-10-06 US disclosed
US-20110242443-A1 PIXEL ELECTRODE PANEL, A LIQUID CRYSTAL DISPLAY PANEL ASSEMBLY AND METHODS FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-10-06 US disclosed