Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 5/20 | 0.65 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | GALR3 | O60755 | 2/20 | 0.65 |
| ▸ | LDHA | P00338 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | ALPG | P10696 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL27970002 | 0.91 | EGFR (0.59) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| SCHEMBL12199178 | 0.86 | SMN1; SMN2 (0.77) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| SCHEMBL170193 | 0.82 | LMNA (0.97) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| SCHEMBL16259077 | 0.81 | EGFR (0.59) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| Hydrochloric Acid SCHEMBL8522254 | 0.80 | SMN1; SMN2 (0.94) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| SCHEMBL15922842 | 0.80 | LMNA (1.00) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| SCHEMBL31197370 | 0.80 | LMNA (1.00) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| SCHEMBL15923566 | 0.80 | LMNA (1.00) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| SCHEMBL11261445 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAS1PR2NPSR1EGFR | |
| SCHEMBL11244483 | 0.79 | LDHA (0.74) | SMN1; SMN2LMNAS1PR2NPSR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362003-B | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| US-20230159446-A1 | Methods and Compositions for Targeting Tregs using CCR8 Inhibitors | NANJING IMMUNOPHAGE BIOMEDICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230038589-A1 | Methods and compositions for targeting Tregs using CCR8 inhibitors | Nanjing Immunophage Biotech Co., Ltd. (CN) | 2023-02-09 | — | — | US | disclosed |
| WO-2012027495-A1 | PIPERAZINYLPYRIMIDINE ANALOGUES AS PROTEIN KINASE INHIBITORS | UNIVERSITY OF THE PACIFIC (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159446-A1 | Methods and Compositions for Targeting Tregs using CCR8 Inhibitors | CCR8, CCR1, CCR3 | SMN1; SMN2 4731/4885LMNA 4214/4885S1PR2 455/4885 |
| US-20230038589-A1 | Methods and compositions for targeting Tregs using CCR8 inhibitors | CCR8, CCR1, CCR3 | SMN1; SMN2 4731/4885LMNA 4214/4885S1PR2 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.