SCHEMBL12200067

SCHEMBL12200067

COc1ccc(S(=O)(=O)c2ccc(Oc3ccc(C(C)(C)c4ccc(Oc5ccc(S(=O)(=O)c6ccc(Oc7ccc(-c8ccc(C)cc8)cc7)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PKM P14618 2/20 0.53
HSD11B1 P28845 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
GAA P10253 2/20 0.46
RAPGEF4 Q8WZA2 1/20 0.46
ACHE P22303 2/20 0.45
BCHE P06276 1/20 0.45
KDM4E B2RXH2 1/20 0.43
MAPT P10636 2/20 0.43
MMP2 P08253 4/20 0.42
MMP9 P14780 4/20 0.42
MMP8 P22894 4/20 0.42
MMP12 P39900 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10093718 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL4548600 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL13910298 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL686036 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL12305031 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL680468 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL10027696 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL14148707 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL16606654 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL10267118 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180044524-A1 MISCIBLE POLYPHENYLENE ETHER SULFONE/POLYALKYLENE TEREPHTHALATE BLENDS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2018-02-15 US disclosed
US-20170084394-A1 Polyetherimide Compatible Polymer Blends for Capacitor Films SABIC GLOBAL TECHNOLOGIES, B.V. (NL) 2017-03-23 US disclosed
US-9074093-B2 Blends of polyphenylene ether sulfone and polyester carbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-07-07 US disclosed
US-9045640-B2 Blends of polyphenylene ether sulfone and silicone polyester carbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-06-02 US disclosed
US-20140039103-A1 BLENDS OF POLYPHENYLENE ETHER SULFONE AND SILICONE POLYESTER CARBONATE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2014-02-06 US disclosed
US-8501291-B2 Sterilized polyetherimide/polyphenylene ether sulfone articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-08-06 US disclosed
US-20130150507-A1 BLENDS OF POLYPHENYLENE ETHER SULFONE AND POLYESTER CARBONATE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-06-13 US disclosed
US-20120308777-A1 STERILIZED POLYETHERIMIDE /POLYPHENYLENE ETHER SULFONE ARTICLES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-12-06 US disclosed
US-8034857-B2 Polyetherimide/polyphenylene ether sulfone blends SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-10-11 US disclosed
US-20090018242-A1 POLYETHERIMIDE/POLYPHENYLENE ETHER SULFONE BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2009-01-15 US disclosed
US-20090018265-A1 POLYETHERIMIDE/POLYPHENYLENE ETHER SULFONE BLENDS GENERAL ELECTRIC COMPANY (US) 2009-01-15 US disclosed