SCHEMBL680468

SCHEMBL680468

COc1ccc(C(C)(C)c2ccc(Oc3ccc(S(=O)(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
PKM P14618 2/20 0.58
HSD11B1 P28845 1/20 0.55
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 4/20 0.50
GAA P10253 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
RAPGEF4 Q8WZA2 1/20 0.49
ACHE P22303 2/20 0.48
BCHE P06276 1/20 0.48
MAPT P10636 2/20 0.46
MMP2 P08253 2/20 0.45
MMP9 P14780 2/20 0.45
MMP8 P22894 2/20 0.45
MMP12 P39900 2/20 0.45
MMP13 P45452 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16606654 1.00 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL26998863 1.00 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL14148707 1.00 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL10027696 1.00 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL10267118 1.00 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL686036 0.96 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL13910298 0.96 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL12200067 0.96 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL12305031 0.96 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL4548600 0.96 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026083-A1 Bioactive compound immobilization on sulfone polymers SYENSQO SPECIALTY POLYMERS USA, LLC 2024-01-25 US disclosed
US-20230399468-A1 BIO-BASED SULFONE COPOLYMERS FREE OF BPA AND BPS SYENSQO SPECIALTY POLYMERS USA, LLC 2023-12-14 US disclosed
US-20230399468-A1 BIO-BASED SULFONE COPOLYMERS FREE OF BPA AND BPS SYENSQO SPECIALTY POLYMERS USA, LLC 2023-12-14 US disclosed
US-20230374221-A1 PROCESS FOR THE MANUFACTURE OF SULFONATED POLYARLYENE(ETHER) SULFONES BASF SE (DE) 2023-11-23 US disclosed
EP-3230986-B1 POLY(ARYL ETHER) COMPOSITIONS FOR POLYMER-METAL JUNCTIONS AND POLYMER-METAL JUNCTIONS AND CORRESPONDING FABRICATION METHODS SOLVAY SPECIALTY POLYMERS USA (US) 2023-11-22 EP disclosed
US-11807757-B2 Economical multi-scale reinforced composites RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-11-07 US disclosed
US-11807757-B2 Economical multi-scale reinforced composites RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-11-07 US disclosed
US-20230348696-A1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-02 US disclosed
US-20230348696-A1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-02 US disclosed
US-20230338902-A1 DIFFUSION TRANSFER FUNCTIONALIZED MEMBRANE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-10-26 US disclosed
US-20070199891-A1 Separation Membrane With Selective Permeability And Process For Producing The Same TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-08-30 US disclosed
US-20070187320-A1 Polysulfone-base permselective hollow fiber membrane bundle and process for producing the same TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-08-16 US disclosed
US-20070166591-A1 POLYMER ELECTROLYTE COMPOSITION AND APPLICATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-19 US disclosed
US-7229580-B2 blending a polyphenylene oxide or polysulfone with a polyimide by selectively decomposing the polyimide phase using monoethanolamine or tetramethylammonium hydroxide; narrow pore size distribution; makes membranes for fluid separations, such as microfiltration, ultrafiltration, and gas separation POROGEN CORPORATION (US) 2007-06-12 US disclosed
US-20070123692-A1 POLYSULFONE COMPOSITIONS EXHIBITING VERY LOW COLOR AND HIGH LIGHT TRANSMITTANCE PROPERTIES AND ARTICLES MADE THEREFROM SOLVAY ADVANCED POLYMERS, LLC (US) 2007-05-31 US disclosed
US-20070114167-A1 Bundle of selectively permeable polysulfone-based hollow fiber membranes and process for manufacturing same TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-05-24 US disclosed
US-20070102372-A1 Polysulfone and poly(N-vinyl lactam) polymer alloy and fiber and filter materials made of the alloy DONALDSON COMPANY, INC. 2007-05-10 US disclosed
US-20070066759-A1 Block copolymers and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
US-7189782-B2 Thermoplastic film, thermoplastic resin composition, and phyllosilicate TEIJIN LIMITED (JP) 2007-03-13 US disclosed
US-7169702-B2 Polysulfone compositions exhibiting very low color and high light transmittance properties and articles made therefrom SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338902-A1 DIFFUSION TRANSFER FUNCTIONALIZED MEMBRANE TRAP1, HSPBP1, HSPH1 HTT 86/4885SMN1; SMN2 3013/4885PKM 1426/4885
US-20240026083-A1 Bioactive compound immobilization on sulfone polymers PLG, PHOSPHO1, FGB HTT 4239/4885SMN1; SMN2 3957/4885PKM 724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.