SCHEMBL686036

SCHEMBL686036

COc1ccc(C(C)(C)c2ccc(Oc3ccc(S(=O)(=O)c4ccc(-c5ccc(S(=O)(=O)c6ccc(C)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PKM P14618 2/20 0.53
HSD11B1 P28845 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
GAA P10253 2/20 0.46
RAPGEF4 Q8WZA2 1/20 0.46
ACHE P22303 2/20 0.45
BCHE P06276 1/20 0.45
KDM4E B2RXH2 1/20 0.43
MAPT P10636 2/20 0.43
MMP2 P08253 4/20 0.42
MMP9 P14780 4/20 0.42
MMP8 P22894 4/20 0.42
MMP12 P39900 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10093718 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL4548600 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL12200067 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL13910298 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL12305031 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL680468 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL10027696 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL14148707 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL16606654 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL10267118 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399468-A1 BIO-BASED SULFONE COPOLYMERS FREE OF BPA AND BPS SYENSQO SPECIALTY POLYMERS USA, LLC 2023-12-14 US disclosed
US-20230399468-A1 BIO-BASED SULFONE COPOLYMERS FREE OF BPA AND BPS SYENSQO SPECIALTY POLYMERS USA, LLC 2023-12-14 US disclosed
EP-3389877-B1 MULTILAYER ASSEMBLY SOLVAY SPECIALTY POLYMERS IT (IT) 2023-04-26 EP disclosed
US-20220297066-A1 PURIFICATION METHODS COMPRISING THE USE OF MEMBRANES OBTAINED FROM BIO-BASED SULFONE POLYMERS SOLVAY SPECIALITY POLYMERS USA, LLC 2022-09-22 US disclosed
EP-3481800-B1 PROCESS FOR PREPARING AN ORGANIC SULFONE BASF SE (DE) 2020-08-05 EP disclosed
EP-3430076-B1 COMPOSITION AND METHOD FOR MANUFACTURING SULFONE POLYMER MEMBRANE SOLVAY SPECIALTY POLYMERS IT (IT) 2020-07-15 EP disclosed
EP-3022254-B1 SEPARATION OF A POLYARYLENE ETHER SOLUTION BASF SE (DE) 2020-02-26 EP disclosed
US-10544303-B2 High performance polymer composition for mobile electronic devices SOLVAY SPECIALITY POLYMERS USA, LLC. (US) 2020-01-28 US disclosed
EP-2181159-B1 BLENDS OF AROMATIC POLYIMIDES AND AROMATIC SULFONE POLYMERS SOLVAY SPECIALTY POLYMERS USA (US) 2019-11-13 EP disclosed
EP-3189092-B1 SULFONE POLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS USA (US) 2019-07-10 EP disclosed
US-20080206536-A1 Poly (Aryl Ether Sulfone) Material And Use Thereof SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2008-08-28 US disclosed
US-20080206536-A1 Poly (Aryl Ether Sulfone) Material And Use Thereof SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2008-08-28 US disclosed
US-20080193702-A1 Poly(Aryletherdisulfone) Composition and Shaped Article Made Thereof SOLVAY ADVANDED POLYMERS, L.L.C. (US) 2008-08-14 US disclosed
US-20080193702-A1 Poly(Aryletherdisulfone) Composition and Shaped Article Made Thereof SOLVAY ADVANDED POLYMERS, L.L.C. (US) 2008-08-14 US disclosed
US-20080064801-A1 Aromatic High Glass Transition Temperature Sulfone Polymer Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2008-03-13 US disclosed
US-20080064801-A1 Aromatic High Glass Transition Temperature Sulfone Polymer Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2008-03-13 US disclosed
US-20080058480-A1 Sulfone Polymer Composition SOLVAY ADVANCED POLYMERS (US) 2008-03-06 US disclosed
US-20080058480-A1 Sulfone Polymer Composition SOLVAY ADVANCED POLYMERS (US) 2008-03-06 US disclosed
US-20070276100-A1 Electronic Components SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-11-29 US disclosed
US-20070276100-A1 Electronic Components SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-11-29 US disclosed