SCHEMBL4548600

SCHEMBL4548600

COc1ccc(S(=O)(=O)c2ccc(Oc3ccc(C(C)(C)c4ccc(-c5ccc(C(C)(C)c6ccc(C)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PKM P14618 2/20 0.53
HSD11B1 P28845 1/20 0.51
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
GAA P10253 2/20 0.46
RAPGEF4 Q8WZA2 1/20 0.46
ACHE P22303 2/20 0.45
BCHE P06276 1/20 0.45
KDM4E B2RXH2 1/20 0.43
MAPT P10636 2/20 0.43
MMP2 P08253 4/20 0.42
MMP9 P14780 4/20 0.42
MMP8 P22894 4/20 0.42
MMP12 P39900 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10093718 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL12200067 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL13910298 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL686036 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL12305031 1.00 HTT (0.55) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL680468 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL10027696 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL14148707 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL16606654 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1
SCHEMBL10267118 0.96 HTT (0.59) HTTSMN1; SMN2PKMHSD11B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9975994-B2 Desalination of polyaryl ethers by means of melt extraction BASF SE (DE) 2018-05-22 US disclosed
US-20180126338-A1 NEW POLYMER COMPOSITIONS BASF SE (DE) 2018-05-10 US disclosed
US-20180056245-A1 PROCESSES FOR REDUCING THE FOULING OF SURFACES BASF SE (DE) 2018-03-01 US disclosed
US-20180009950-A1 DESALINATION OF POLYARYL ETHERS FROM A MELT POLYMERIZATION METHOD BASF SE (DE) 2018-01-11 US disclosed
US-20180009944-A1 DESALINATION OF POLYARYL ETHERS BY MEANS OF MELT EXTRACTION BASF SE (DE) 2018-01-11 US disclosed
US-9828472-B2 Division of a polyarylene ether solution BASF SE (DE) 2017-11-28 US disclosed
US-20170333849-A1 COPOLYMERS FOR MAKING MEMBRANES BASF SE (DE) 2017-11-23 US disclosed
US-9809685-B2 Division of a polyarylene ether solution BASF SE (DE) 2017-11-07 US disclosed
US-20170073467-A1 NEW COPOLYMERS SUITABLE FOR MAKING MEMBRANES BASF SE (DE) 2017-03-16 US disclosed
US-9567463-B2 High-strength blends based on polyarylene ethers BASF SE (DE) 2017-02-14 US disclosed
US-20120296028-A1 THERMOPLASTIC MOLDING COMPOSITION MADE OF POLYARYLENE ETHERS AND POLYPHENYLENE SULFIDE WITH IMPROVED PROCESSING STABILITY BASF SE (DE) 2012-11-22 US disclosed
US-20120296031-A1 BLENDS OF POLYARYLENE ETHERS AND POLYARYLENE SULFIDES BASF SE (DE) 2012-11-22 US disclosed
US-20120108713-A1 BOROPHOSPHATE, BORATE PHOSPHATE, AND METAL BOROPHOSPHATE AS NOVEL FLAME PROOFING ADDITIVES FOR PLASTICS BASF SE (DE) 2012-05-03 US disclosed
US-20120108693-A1 SEGMENTED POLYARYLENE ETHER BLOCK COPOLYMERS BASF SE (DE) 2012-05-03 US disclosed
US-20110237693-A1 Blends made of polyarylene ethers and of polyarylene sulfides BASF SE (DE) 2011-09-29 US disclosed
US-20110224386-A1 REACTIVE POLYARYLENE ETHER AND METHOD FOR THE MANUFACTURE THEREOF BASF SE (DE) 2011-09-15 US disclosed
US-20110218294-A1 BLENDS OF POLYARYLENE ETHERS AND POLYARYLENE SULFIDES BASF SE (DE) 2011-09-08 US disclosed
US-20110201747-A1 BRANCHED POLYARYLENE ETHERS AND THERMOPLASTIC MOLDING COMPOUNDS CONTAINING SAID ETHERS BASF SE (DE) 2011-08-18 US disclosed
US-20100286303-A1 METHOD FOR PRODUCING POLYARYL ETHERS BASF SE (DE) 2010-11-11 US disclosed
US-20100036041-A1 MOLDING MATERIALS COMPRISING HIGHLY CROSSLINKED ORGANIC NANOPARTICLES BASF SE (DE) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180009944-A1 DESALINATION OF POLYARYL ETHERS BY MEANS OF MELT EXTRACTION PHOSPHO1, STS, SLC6A12 HTT 441/4885SMN1; SMN2 1266/4885PKM 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.