Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820693 | 0.87 | TEAD1 (0.58) | GAAALDH1A1KDM4E | |
| SCHEMBL13236630 | 0.87 | S1PR5 (0.66) | L3MBTL1GAAALDH1A1PKMS1PR1 | |
| SCHEMBL14174789 | 0.86 | ALDH1A1 (0.67) | L3MBTL1GAAALDH1A1PKMS1PR1 | |
| SCHEMBL592839 | 0.85 | MEN1 (0.66) | MEN1KMT2A | |
| SCHEMBL31612500 | 0.84 | ALDH1A1 (0.61) | L3MBTL1GAAALDH1A1S1PR1S1PR5 | |
| SCHEMBL14902978 | 0.83 | S1PR1 (0.69) | L3MBTL1ALDH1A1PKMS1PR1S1PR5 | |
| SCHEMBL798026 | 0.83 | MEN1 (0.56) | ALDH1A1S1PR1S1PR5MEN1KMT2A | |
| SCHEMBL12640184 | 0.83 | SIGMAR1 (0.54) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18117051 | 0.81 | S1PR5 (0.71) | L3MBTL1S1PR1S1PR5SMN1; SMN2 | |
| SCHEMBL27895733 | 0.81 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034946-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2011-10-11 | — | — | US | disclosed |