Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206187 | 0.93 | HDAC3 (0.55) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL9188875 | 0.92 | CCR6 (0.66) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL16269680 | 0.87 | ATM (0.48) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL7202865 | 0.85 | CCR6 (0.58) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL7205254 | 0.84 | CCR6 (0.57) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL8619042 | 0.84 | ATM (0.45) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL7202274 | 0.83 | CCR6 (0.56) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL7207519 | 0.83 | CCR6 (0.56) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL15613005 | 0.79 | SMN1; SMN2 (0.55) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL9102803 | 0.78 | ATM (0.52) | HDAC3HDAC1HDAC2NCOR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501478-B2 | Trehalose click polymers for delivery of biologically active molecules | UNIVERSITY OF CINCINNATI (US) | 2013-08-06 | — | — | US | disclosed |
| US-8372966-B2 | Oligonucleotide decoys and methods of use | UNIVERSITY OF CINCINNATI (US) | 2013-02-12 | — | — | US | disclosed |
| US-8034619-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2011-10-11 | — | — | US | disclosed |
| US-7927873-B2 | Polyamides for nucleic acid delivery | UNIVERSITY OF CINCINNATI (US) | 2011-04-19 | — | — | US | disclosed |
| US-20090124534-A1 | Trehalose Click Polymers for Delivery of Biologically Active Molecules | UNIVERSITY OF CINCINNATI (US) | 2009-05-14 | — | — | US | disclosed |
| US-20090105115-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | UNIVERSITY OF CINCINNATI | 2009-04-23 | — | — | US | disclosed |
| US-20090099108-A1 | OLIGONUCLEOTIDE DECOYS AND METHODS OF USE | UNIVERSITY OF CINCINNATI | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105115-A1 | POLYAMIDES FOR NUCLEIC ACID DELIVERY | TLR3, TLR9, TLR6 | CCR6 190/4885PAX8 4395/4885HDAC3 95/4885 |
| US-20090124534-A1 | Trehalose Click Polymers for Delivery of Biologically Active Molecules | TREH, TK1, DDOST | CCR6 2089/4885PAX8 2212/4885HDAC3 1913/4885 |
| US-20090099108-A1 | OLIGONUCLEOTIDE DECOYS AND METHODS OF USE | NFKB2, IKBKB, NFKBIA | CCR6 1342/4885PAX8 488/4885HDAC3 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.