Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12202047 | 0.83 | MEN1 (0.40) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL24013661 | 0.83 | MEN1 (0.40) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL29453648 | 0.78 | CES2 (0.52) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL15853708 | 0.78 | CES2 (0.52) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL1998132 | 0.78 | CES2 (0.52) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL17947416 | 0.78 | CES2 (0.52) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL30134348 | 0.77 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL17215607 | 0.77 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL30809607 | 0.77 | CA3 (0.48) | MEN1KMT2APDE2ACES2CES1 | |
| SCHEMBL24869041 | 0.77 | MEN1 (0.41) | MEN1KMT2APDE2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |